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Total result(s) found: 14
  • ​Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) study
    S. Hägg, J. Skogsberg, J. Lundström, P. Noori, R. Nilsson, H. Zhong, S. Maleki, M.-M. Shang, B. Brinne, M. Bradshaw, V.B. Bajic, (…), J. Tegnér, J. Björkegren
    PLoS Genet, 5(12):e1000754, 2009
Keywords:
Lim domain binding 2; Messenger RNA; Transcription factor; Unclassified drug; Gene expression profiling; Genetic transcription
  • ​The transcriptional network controls growth arrest and differentiation in a human myeloid leukemia cell line
    The FANTOM consortium and RIKEN Genome Exploration Research Group: H. Suzuki et al.
    Nature Genetics, 41(5):553-62, 2009
Keywords:
Base sequence; Cell differentiation; Cell proliferation; Gene expression profiling; Gene regulatory networks; Leukemia, Molecular sequence data
  • ​Deconstructing the core dynamics from a complex time-lagged regulatory biological circuit IET
    O. Eriksson, B. Brinne, Y., Zhou, J. Björkegren, J. Tegnér
    Systems Biology; 3(2):113-29, 2009
Keywords:
Cell cycles; Complex models; Computational biology; Model complexity; Molecular networks; Nonlinear computational models; Protein networks; System analysis
  • ​Bridging the gap between systems biology and medicine
    G. Clermont, C. Auffray, Y. Moreau, D.M. Rocke, D. Dalevi, D. Dubhashi, D.R. Marshall, P. Raasch, F. Dehne, P. Provero, J. Tegnér, B.J. Aronow, M.A. Langston, M. Benson
    Genome Med. Sep 29;1(9):88, 2009
Keywords:
Experimental design; Gene regulatory network; Integrative medicine; Microarray analysis; Priority journal; Protein interaction; Systems biology
  • ​Can modular analysis identify disease-associated candidate genes for therapeutics?
    J. Tegnér
    Journal of Biology, 8:48, 2009
Keywords:
Anti-allergic agents; Automatic data processing; Gene expression profiling; Gene expression regulation; Hypersensitivity
  • ​Computational disease modeling – fact or fiction?
    J. Tegnér, A. Compte, C. Auffray, G. An, G. Cedersund, G. Clermont, B. Gutkin, Z.N. Oltvai, K. Enno Stephan, R. Thomas, P. Villoslada
    Invited meeting report/review, BMC Syst Biol; 3:56, 2009
Keywords:
Biology; Computational Biology; Computer Simulation; Disease; Uncertainty
  • ​Reverse engineering of gene networks with LASSO and non-linear basis functions
    M. Gustafsson, M. Hörnqvist, J. Lundström, J. Björkegren, J. Tegnér
    Annals of the New York Academy of Sciences; 1158:265-75, 2009
Keywords:
DREAM conference; LARS; LASSO; Network inference; Nonlinear; Reverse engineering
  • ​An algorithm for reading dependencies from the minimal undirected independence map of a graphoid that satisfies weak transitivity
    J. Pena, R. Nilsson, J. Björkegren, and J. Tegnér
    The Journal of Machine Learning Research archive, Volume 10, Pages 1071-1094, 2009
Keywords:
Bioinformaties; Graphical models; Graphoids; Vertex separation; Weak transitivity
  • ​Mechanism for Top-down control of working memory capacity
    F. Edin, T. Klingberg, P. Johansson, F. McNab, J. Tegnér, A. Compte
    Proceedings of National Academy of Science, 106(16):6802-7, 2009
Keywords:
Computer model; fMRI; Lateral inhibition; Parietal; Prefrontal; Short-term memory
  • On reliable discovery of molecular signatures
    R. Nilsson, J. Björkegren and J. Tegnér
    BMC Bioinformatics, 10:38, 2009
Keywords:
Accurate prediction; Cancer gene expression; False discovery rate; Molecular signatures; Predictive accuracy; Signature discovery; Statistical framework; Statistical hypothesis testing
  • ​Genome-wide system analysis reveals stable yet flexible network dynamics in yeast
    M. Gustafsson, M. Hörnkvist, J. Björkegren, and J. Tegnér
    IET Systems Biology, Vol 3, p. 219 – 228, 2009
Keywords:
Cell cycle; Cellular network; Design Principles; Dynamical networks; Expression data; Flexible networks; Gene regulatory networks; Higher-order dynamics; Literature mining; Modular coupling
  • Transcription regulatory network analysis using CAGE
    J. Tegnér, J. Björkegren, T. Ravasi, V. Bajic
    Chapter in Cap Analysis Gene Expression (CAGE) The science of decoding gene transcription, Edited by P. Carcinci, Pan Stanford Publishing, 2009
Keywords:
Network analysis; CAGE; Gene expression
  • ​On stability of limit cycles of a prototype problem of piecewise linear systems
    O. Eriksson, J. Tegnér, and Y. Zhou
    Lecture Notes in Control and Information Sciences, Volume 393, Pages 43-55, 2009
Keywords:
Cell membranes; Delta sigma modulation; Linear systems; Machinery; Nonlinear systems; Piecewise linear techniques
  • ​Networks in Biology – from identification, analysis to interpretation
    J. Tegnér
    In I.G. Tollis and M. Patrignani (Eds.): GD 2008, LNCS 5417, p. 1. Springer-Verlag Berlin Heidelberg, 2009
Keywords:
Biological networks; Medical applications