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Total result(s) found: 10
  • ​Integrative approaches to computational biomedicine
    P.V. Coveney, V. Diaz-Zuccarini, N. Graf, P. Hunter, P. Kohl, J. Tegner, M. Viceconti
    Interface Focus 3 (2), 20130003, 2013
Keywords:
Computational biomedicine; To human health; Virtual physiological human
  • ​An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation 450 BeadChip platform
    F. Marabita, M. Almgren, M.E. Lindholm, S. Ruhrmann, F. Fagerström-Billai, M. Jagodic, C.J. Sundberg, T.J. Ekström, A.E. Teschendorff, J. Tegnér and D. Gomez-Cabrero
    Epigenetics 8(3), 333–46, 2013
Keywords:
DNA methylation; Illumina 450K; Microarray; Normalization; Technical variability
  • Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register
    I. Abugessaisa, D. Gomez-Cabrero, O. Snir, S. Lindblad, L. Klareskog, V. Malmström, J. Tegnér
    Journal of Translational Medicine, 11:85. 11(1), 85, 2013
Keywords:
Patient de-identification; Secondary use of clinical data; Swedish Rheumatology Quality Register (SRQ)
  • ​Pediatric systems medicine: evaluating needs and opportunities using congenital heart block as a case study
    J. Tegnér, I. Abugessaisa
    Pediatric Research, 73, 508–513, 2013
Keywords:
Computational Biology; Genomics; Heart Block; Newborn; Pediatrics; Risk Factors
  • ​A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinum 450k DNA methylation data
    A.E. Teschendorff, F. Marabita, M. Lechner, T. Bartlett, J. Tegnér, D. Gomez-Cabrero, S. Beck
    Bioinformatics; 29(2):189-96, 2013
Keywords:
Algorithms; DNA methylation; Neoplasms; Normal distribution; Nucleic acid probes; Oligonucleotide array sequence analysis
  • Identification of novel markers in rheumatiod arthritis through integrated analysis of DNA methylation and microRNA expression
    L. de la Rica, J.M. Urquiza, D. Gómez-Cabrero, A.B. Islam, N. López-Bigas, J. Tegnér, R.E. Toes, E. Ballestar
    J. Autoimmunity, 41:6-16, 2013
Keywords:
Rheumatoid arthritis; Rheumatoid arthritis synovial fibroblasts; DNA methylation; Epigenetic; MicroRNAs
  • Algorithmic complexity of motifs clusters superfamilies of networks
    H. Zenil, N.A. Kiani, J. Tegnér
    Bioinformatics and Biomedicine (BIBM), IEEE, 74-76, 2013
Keywords:
Algorithmic probability; Complex networks; Information content; Information theory; Kolmogorov complexity; Network motifs; Network typology
  • ​Importance of mitochondrial PO2 in maximal O2 transport and utilization: A theoretical analysis
    I. Cano, M. Mickael, D. Gomez-Cabrero, J. Tegnér, J. Roca, P.D. Wagner
    Respiratory  Physiology & Neurobiology, Pages 477–483, 2013
Keywords:
Bioenergetics; Mitochondrial PO2; Mitochondrial respiration; Oxygen transport; V̇O2max
  • Testing biological models for non-linear sensitivity with a programmability test
    H. Zenil, G. Ball and J. Tegnér
    Advances in Artificial Life,12, ECAL, 2013
Keywords:
Biological models; Non-linear sensitivity; Programmability test
  • A vision and strategy for the virtual physiological human: 2012 update
    P. Hunter, T. Chapman, P.V. Coveney, B. de Bono, V. Diaz, J. Fenner, A.F. Frangi, P. Harris, R. Hose, P. Kohl, P. Lawford, K. McCormack, M. Mendes, S. Omholt, A. Quarteroni, N. Shublaq, J. Skår, K. Stroetmann, J. Tegnér, (...) and M. Viceconti
    Interface Focus, Vol. 3 No. 220130004, 2013
Keywords:
Computational physiology; Multiscale modelling; Physiome; Systems biology; Virtual physiological human