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  • ​Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition
    V. Rodríguez-Cortez, L. Pino-Molina, J. Rodríguez-Ubreva, L. Ciudad, D. Gómez-Cabrero, C. Company, J. Urquiza, J. Tegnér, C. Rodríguez-Gallego, E. López-Granados, E. Ballestar
    Nature Communications, Volume 6, Article number 7335, 2015
DNA; Gene expression; Germ cell; Memory; Methylation
  • ​VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients
    X. Yang, Y. Zhang, K. Hosaka, P. Andersson, J. Wang, F. Tholander, Z. Cao, H. Morikawa, J. Tegnér, Y. Yang, H. Iwamoto, S. Lim, Y. Cao
    Proceedings of National Academy of Science 5/19, 2015
Angiogenesis; Metastasis; VEGF-A; VEGF-B; VEGFR1
  • ​IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3
    R.K.W. Mailer, A.-L. Joly, S. Liu, S. Elias, J. Tegnér, J. Andersson
    Scientific Reports, Volume 5, Article number 14674, 2015
Crohn's disease; Interleukins; Peripheral tolerance; Transcription
  • ​The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation
    Reiner K.W. Mailer, A.-L. Joly, S. Liu, Sz. Elias, J. Tegnér, J. Andersson
    Scientific Reports, Volume 5, Article number 15029, 2015
Cell proliferation, Cancer metabolism; Computational models
  • Laboratory biomarkers and frailty: presentation of the frailomic initiative
    G. Lippi, P. Jansen-Duerr, J. Viña, A. Durrance-Bagale, I. Abugessaisa, D. Gomez-Cabrero, J. Tegnér, J. Grillari, J. Erusalimsky, A. Sinclair, L. Rodriguez-Manãs, FRAILOMIC consortium
    Clinical Chemistry and Laboratory Medicine, 1;53(10): e253-5 2015
Ageing; Biomarkers; Frailty; Sarcopenia
  • ​Signaling networks in MS: A systems-based approach to developing new pharmacological therapies
    E. Kotelnikova, M. Bernardo-Faura, G. Silberberg, N.A. Kiani, D. Messinis, I.N. Melas, L. Artigas, E. Schwartz, I. Mazo, M. Masso, L.G. Alexopoulos, J. Manuel Mas, T. Olsson, J. Tegnér, R. Martin, A. Zamora, F. Paul, J. Saez-Rodriguez, P. Villoslada
    Mult. Scler. 21(2):138-46, 2015
Drug discovery; Multiple sclerosis; Pathways; Signaling; Systems biology
  • ​DNA methylation: an epigenetic marker of breast cancer influenced by nutrients acting as an environmental factor
    T.N. Hasan, G. Shafi, B. Leena Grace, J. Tegnér, A. Munshi
    Chapter in Noninvasive Molecular Markers in Gynecologic Cancers, 191-210, CRC Press, 2015
DNA; DNA Methylation; Epigenetics; Breast canser
  • ​Introduction to data types in epigenomics
    F. Marabita, J. Tegnér, D. Gomez-Cabrero
    Chapter in Computational and Statistical Epigenomics, pp3-34, Springer, 2015
Epigenomics DNA; Methylation; Histone modifications; ChIP-seq; Bioinformatics
  • ​Numerical investigation of graph spectra and information interpretability of eigenvalues
    H. Zenil, N.A. Kiani, J. Tegnér
    Bioinformatics and Biomedical Engineering, Lecture Notes in Bioinformatics, 395-405, 2015
Algorithmic complexity; Algorithmic probability; Eigenvalues meaning; Graph spectra behavior; Information content; Network science
  • ​Approximations of algorithmic and structural complexity validate cognitive-behavioural experimental results
    H. Zenil, J.A.R. Marshall, J. Tegnér
    arXiv:1509.06338, 2015
Behavioural biases; Ant behaviour; Mouse behaviour; Drosophila behaviour; Communication complexity; Tradeoffs of complexity measures; Shannon Entropy; Kolmogorov-Chaitin complexity; Logical Depth