News

DNA and RNA are fundamental molecules encoding the building plan of every living organism. Sequencing methods for DNA and RNA have become ubiquitous tools for the life sciences and healthcare. For example, sequencing has opened up entirely new avenues of research in diverse fields, such as the study of evolution or the understanding of the molecular mechanisms of complex diseases like cancer.

​The principle of maximum entropy (Maxent) is often used to obtain prior probability distributions as a method to obtain a Gibbs measure under some restriction giving the probability that a system will be in a certain state compared to the rest of the elements in the distribution...

​​Multiple sclerosis (MS), a leading cause of neurological disability in young adults, is a chronic inflammatory and neurodegenerative disease of the central nervous system (CNS) characterized by autoimmune destruction of myelin and subsequent neuronal death...

​Dysregulation of signaling pathways in multiple sclerosis (MS) can be analyzed by phosphoproteomics in peripheral blood mononuclear cells (PBMCs).

​The differentiation of self-renewing progenitor cells requires not only the regulation of lineage- and developmental stage–specific genes but also the coordinated adaptation of housekeeping functions from a metabolically active, proliferative state toward quiescence...

Napping behind the wheel, SPACE FORCE, and AI thinking abstractly

We have made progress on developing an AI system that thinks like a scientist – published in Nature Machine Intelligenc

The lab is now staffed with very skilled members, with different and complementary backgrounds, and we are particularly excited about the talented students who are currently in the lab. The reconstruction of the experimental lab is close to be finished.

During 2018 the team published 21 papers, including papers in Nature Communication, Human Molecular Genetics, and BMC Biology.

We have made exciting advances during the last years in fundamental algorithmic information theory where we develop new theory, algorithm, and practical applications.

We have designed a new course on Computational Bioscience and Machine Learning, which was given in 2018 for the first time.

During 2017 the team published 18 papers. Some highlights include an editorial and paper in a special issue of Current Opinion in Systems Biology targeting recent progress and challenges in systems medicine.

​​Manjula Thimma will represent the team in the first FANTOM6 meeting (Japan) on non-coding RNA in September.
Jesper Tegner is a co-organizer of the second workshop on “Computational Methods for Cytometry and Single-Cell Data", Crete, Greece.

Peri Noori enters our team. She has decades of broad and deep experience in methods of molecular biology and their applications. From protocol development, to a well functioning high-end laboratory.

Dr. Hiromasa Morikawa arrives to the team providing broad and deep expertise on single cell genomics w.r.t experiments, bioinformatics, and the clinic.
Ghada Albeik, our research assistant, fires up our molecular laboratory.

​We welcome Dr. Manjula Thimma as our first official lab member. She brings crucial informatics expertise serving as our senior bioinformatics leader.