Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition

Year:2015
Authors: V. Rodríguez-Cortez, L. Pino-Molina, J. Rodríguez-Ubreva, L. Ciudad, D. Gómez-Cabrero, C. Company, J. Urquiza, J. Tegnér, C. Rodríguez-Gallego, E. López-Granados, E. Ballestar
DNA Gene expression Germ cell Memory Methylation

VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients

Year:2015
Authors: X. Yang, Y. Zhang, K. Hosaka, P. Andersson, J. Wang, F. Tholander, Z. Cao, H. Morikawa, J. Tegnér, Y. Yang, H. Iwamoto, S. Lim, Y. Cao
Angiogenesis Metastasis VEGF-A VEGF-B VEGFR1

IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3

Year:2015
Authors: R.K.W. Mailer, A.-L. Joly, S. Liu, S. Elias, J. Tegnér, J. Andersson
Crohn's disease Interleukins Peripheral tolerance Transcription

The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation

Year:2015
Authors: Reiner K.W. Mailer, A.-L. Joly, S. Liu, Sz. Elias, J. Tegnér, J. Andersson
Cell proliferation Cancer metabolism Computational models

Laboratory biomarkers and frailty: presentation of the frailomic initiative

Year:2015
Authors: G. Lippi, P. Jansen-Duerr, J. Viña, A. Durrance-Bagale, I. Abugessaisa, D. Gomez-Cabrero, J. Tegnér, J. Grillari, J. Erusalimsky, A. Sinclair, L. Rodriguez-Manãs, FRAILOMIC consortium
Ageing Biomarkers Frailty Sarcopenia

Signaling networks in MS: A systems-based approach to developing new pharmacological therapies

Year:2015
Authors: E. Kotelnikova, M. Bernardo-Faura, G. Silberberg, N.A. Kiani, D. Messinis, I.N. Melas, L. Artigas, E. Schwartz, I. Mazo, M. Masso, L.G. Alexopoulos, J. Manuel Mas, T. Olsson, J. Tegnér, R. Martin, A. Zamora, F. Paul, J. Saez-Rodriguez, P. Villoslada
Drug discovery Multiple sclerosis Pathways Signaling Systems biology

DNA methylation: an epigenetic marker of breast cancer influenced by nutrients acting as an environmental factor

Year:2015
Authors: T.N. Hasan, G. Shafi, B. Leena Grace, J. Tegnér, A. Munshi
DNA DNA methylation Epigenetics Breast canser

Introduction to data types in epigenomics

Year:2015
Authors: F. Marabita, J. Tegnér, D. Gomez-Cabrero
Epigenomics DNA Methylation Histone modifications ChIP-seq Bioinformatics

Numerical investigation of graph spectra and information interpretability of eigenvalues

Year:2015 ISSN:03029743
Authors: H. Zenil, N.A. Kiani, J. Tegnér
Algorithmic complexity Algorithmic probability Eigenvalues meaning Graph spectra behavior Information content Network science

Approximations of algorithmic and structural complexity validate cognitive-behavioural experimental results

Year:2015
Authors: H. Zenil, J.A.R. Marshall, J. Tegnér
Behavioural biases Ant behaviour Mouse behaviour Drosophila behaviour Communication complexity Tradeoffs of complexity measures Shannon Entropy Kolmogorov-Chaitin complexity Logical Depth
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