Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes

Authors: J. Skogsberg, J. Lundström, A. Kovacs, R. Nilsson, P. Noori, S. Maleki, M. Köhler, A. Hamsten, J. Tegnér, J. Björkegren
Apolipoprotein B-100 Atherosclerosis Carrier proteins Cholesterol Foam cells Gene Expression Profiling Macrophages Mutant strains

Evidence of highly regulated genes (in-hubs) in gene networks of Saccharomyces cerevisiae

Authors: J. Lundström, J. Björkegren J. Tegnér
Gene expression Network Algorithm Transcription regulation Protein-protein interactions In-hubs

ApoB100-LDL Acts as a metabolic signal from liver to peripheral fat causing inhibition of lipolysis in adipocytes

Authors: J. Skogsberg, A. Dicker, M. Rydén, G. Åström, R. Nilsson, A. Mairal, D. Langin, P. Alberts, E. Walum, J. Tegnér, A. Hamsten, P. Arner, J. Björkegren
ApoB100-LDL Cholesterol blood level Energy metabolism lipolysis Metabolic syndrome X

Electrotonic signals along intracellular membranes may interconnect dendritic spines and nucleus

Authors: I. Sheemer, B. Brinne, J. Tegnér, S. Grillner
Action potentials Cell nucleus Computer simulation Endoplasmic reticulum Intracellular membranes Synaptic transmission

Integrated approaches to uncovering transcription regulatory networks in mammalian cells

Authors: K. Tan, J. Tegnér, T. Ravasi
Bioinformatics Cellular networks ChIp-chip Dynamics Gene expression Gene networks Genomics Networks Personalized medicine Protein interaction maps Protein-protein interaction networks Systems biology

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