Hiromasa Morikawa, PhD

Research Interests

T-cell immunology (in particular, regulatory T-cells) with molecular biological methods.
Computational analysis on biological data (in particular on single cell data)
Cancer therapy (in particular, lung cancer) and Transplantation (in particular, lung transplantation

Selected Publications

FANTOM5 CAGE profiles of human and mouse samples
S. Noguchi, (…), H. Morikawa, H. Kawaji, P. Carninci, A. Forrest, Y. Hayashizaki
Scientific Data, In press, (2017)
VEGF-B promotes cancer metastasis through a VEGF-A-independent mechanism and serves as a marker of poor prognosis for cancer patients
X. Yang, Y. Zhang, K. Hosaka, P. Andersson, J. Wang, F. Tholander, Z. Cao, H. Morikawa, J. Tegnér, (…) Y. Cao
Proc Natl Acad Sci U S A. 112(22): E2900-2909, (2015)
Genetic and epigenetic basis of Treg cell development and function: From a FoxP3-centered view to an epigenome-defined view of natural Treg cells
H. Morikawa, S. Sakaguchi
Immunol Rev. 259(1):192-205, (2014)
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
Y. Ito, M. Hashimoto, K. Hirota, N. Ohkura, H. Morikawa, H. Nishikawa, A. Tanaka, M. Furu, H. Ito, T. Fujii, (…), S. Sakaguchi
Science. 6207(346): 363-368, (2014)
Continuous T cell receptor signals maintain a functional regulatory T cell pool
J.C. Vahl, C. Drees, K. Heger, S. Heink, C. Fischer Julius, J. Nedjic, N. Ohkura, H. Morikawa, (…), M. Schmidt-Supprian
Immunity. 5(41):722-736, (2014)
A promoter level mammalian expression atlas
A. Forrest., H. Kawaji., (…), H. Morikawa (…), Y. Hayashizaki
Nature. ;507(7493):462-70, (2014)
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
H. Morikawa, N. Ohkura, A. Vandenbon, (...), S. Sakaguchi
Proc Natl Acad Sci U S A. 111(14): 5289-94, (2014)
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
T. Yamaguchi, A. Kishi, M. Osaki, H. Morikawa, (…), S. Sakaguchi
Proc Natl Acad Sci U S A. 110(23): E2116–25, (2013)
T Cell receptor stimulation-induced epigenetic changes and foxp3 expression are independent and complementary events required for treg cell development
N. Ohkura, M. Hamaguchi, H. Morikawa, (…), S. Sakaguchi
Immunity. 16(37):785-799, (2012)

Education

Ph.D., Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2013
M.D., Kyoto University Medical School, Kyoto, Japan, 200

Professional Profile

2017 — Present: Research Consultant , King Abdullah University of Science & Technology, Saudi Arabia2015 – Present : Vinnmer-Marie Curie Fellow, Unit of Computational Medicine, Karolinska Institutet, Stockholm, Sweden
2014 – 2014: Postdoctoral fellow, Unit of Computational Medicine, Karolinska Institutet, Stockholm, Sweden
2014 – 2014: Assistant Professor / Research Unit Co-leader, Immunology Frontier Research Center, Osaka University, Osaka, Japan
2012 – 2014: Specially appointed researcher, Immunology Frontier Research Center, Osaka University, Osaka, Japan
2004 – 2008: Medical Doctor, Department of Thoracic Surgery, National Hospital Organization Nagara Medical Center, Gifu, Japan
2002 – 2004: Medical Doctor, Department of Thoracic Surgery, Fukui Redcross Hospital, Fukui, Japan
2001 – 2002: Medical Doctor, Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japa

Scientific and Professional Membership

2012 – 2022 Board Member of The Japanese Association for Chest Surgery

KAUST Affiliations

Biological and Environmental Sciences and Engineering (BESE)

Research Interests Keywords

Immunology Oncology Single cell analysis Bioinformatics

Hiromasa Morikawa, PhD

Research Interests

Selected Publications

Education

Professional Profile

Scientific and Professional Membership

KAUST Affiliations

Research Interests Keywords

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